Botulinum Toxin Injection Pain Is Less with Smaller-Gauge Needles

By Will Boggs MD

NEW YORK (Reuters Health) - Injection of botulinum toxin type A through 32-gauge needles is slightly less painful than injection through 30-gauge needles, according to a randomized trial.

Dermatologists routinely use 30-gauge needles for facial injections of neurotoxins, prepackaged fillers, and intralesional local anesthesia, but pain is still an issue even with these small-gauge needles.



Urodynamic testing: Is it a useful tool in the management of children with cutaneous stigmata of occult spinal dysraphism?

Lavallée LT, Leonard MP, Dubois C, Guerra LA; Journal of Urology (Sep 2012)

Source: J Urol  

PURPOSE:  Lumbar cutaneous stigmata in infants may be associated with occult spinal dysraphism and often trigger urologic evaluation including urodynamic testing. We examined whether urodynamic testing is useful in this population by evaluating the association between abnormal urodynamic test results and need for tethered cord release. 



I-ADD Study: Assessment of Efficacy and Safety Profile of Irbesartan/Amlodipine Fixed-Dose Combination Therapy Compared With Irbesartan Monotherapy in Hypertensive Patients Uncontrolled With Irbesartan 150 mg Monotherapy: A Multicenter, Phase III, Prospec

Bobrie G, I-ADD Study Investigators; Clinical Therapeutics (Jul 2012)

Source: Clin Ther







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